Asthma and its relationship to mitochondrial copy number: Results from the Asthma Translational Genomics Collaborative (ATGC) of the Trans-Omics for Precision Medicine (TOPMed) program

BACKGROUND: Mitochondria support critical cellular functions, such as energy production through oxidative phosphorylation, regulation of reactive oxygen species, apoptosis, and calcium homeostasis. OBJECTIVE: Given the heightened level of cellular activity in patients with asthma, we sought to deter...

Descripción completa

Detalles Bibliográficos
Autores principales: Cocco, Maxwell P., White, Evan, Xiao, Shujie, Hu, Donglei, Mak, Angel, Sleiman, Patrick, Yang, Mao, Bobbitt, Kevin R., Gui, Hongsheng, Levin, Albert M., Hochstadt, Samantha, Whitehouse, Kyle, Rynkowski, Dean, Barczak, Andrea J., Abecasis, Gonçalo, Blackwell, Thomas W., Kang, Hyun Min, Nickerson, Deborah A., Germer, Soren, Ding, Jun, Lanfear, David E., Gilliland, Frank, Gauderman, W. James, Kumar, Rajesh, Erle, David J., Martinez, Fernando, Hakonarson, Hakon, Burchard, Esteban G., Williams, L. Keoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688161/
https://www.ncbi.nlm.nih.gov/pubmed/33237978
http://dx.doi.org/10.1371/journal.pone.0242364

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688161/
https://www.ncbi.nlm.nih.gov/pubmed/33237978
http://dx.doi.org/10.1371/journal.pone.0242364

Ejemplares similares