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PD-L1 Reverse Signaling in Dermal Dendritic Cells Promotes Dendritic Cell Migration Required for Skin Immunity

Although the function of the extracellular region of programmed death ligand 1 (PD-L1) through its interactions with PD-1 on T cells is well studied, little is understood regarding the intracellular domain of PD-L1. Here, we outline a major role for PD-L1 intracellular signaling in the control of de...

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Detalles Bibliográficos
Autores principales: Lucas, Erin D., Schafer, Johnathon B., Matsuda, Jennifer, Kraus, Madison, Burchill, Matthew A., Tamburini, Beth A. Jirón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688291/
https://www.ncbi.nlm.nih.gov/pubmed/33053342
http://dx.doi.org/10.1016/j.celrep.2020.108258