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BLOS1 mediates kinesin switch during endosomal recycling of LDL receptor

Low-density lipoprotein receptor (LDLR) in hepatocytes plays a key role in plasma clearance of circulating LDL and in whole body cholesterol homeostasis. The trafficking of LDLR is highly regulated in clathrin-dependent endocytosis, endosomal recycling and lysosomal degradation. Current studies focu...

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Detalles Bibliográficos
Autores principales: Zhang, Chang, Hao, Chanjuan, Shui, Guanghou, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688313/
https://www.ncbi.nlm.nih.gov/pubmed/33179593
http://dx.doi.org/10.7554/eLife.58069