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Proteomic analysis of young and old mouse hematopoietic stem cells and their progenitors reveals post-transcriptional regulation in stem cells

The balance of hematopoietic stem cell (HSC) self-renewal and differentiation is critical for a healthy blood supply; imbalances underlie hematological diseases. The importance of HSCs and their progenitors have led to their extensive characterization at genomic and transcriptomic levels. However, t...

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Detalles Bibliográficos
Autores principales: Zaro, Balyn W, Noh, Joseph J, Mascetti, Victoria L, Demeter, Janos, George, Benson, Zukowska, Monika, Gulati, Gunsagar S, Sinha, Rahul, Flynn, Ryan A, Banuelos, Allison, Zhang, Allison, Wilkinson, Adam C, Jackson, Peter, Weissman, Irving L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688314/
https://www.ncbi.nlm.nih.gov/pubmed/33236985
http://dx.doi.org/10.7554/eLife.62210