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Protein-avoidant ionic liquid (PAIL)–coated nanoparticles to increase bloodstream circulation and drive biodistribution

The rapid clearance of intravenously administered nanoparticles (NPs) from the bloodstream is a major unsolved problem in nanomedicine. Here, we describe the first use of biocompatible protein-avoidant ionic liquids (PAILs) as NP surface modifiers to reduce opsonization. An ionic liquid choline hexe...

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Detalles Bibliográficos
Autores principales: Hamadani, Christine M., Goetz, Morgan J., Mitragotri, Samir, Tanner, Eden E. L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688330/
https://www.ncbi.nlm.nih.gov/pubmed/33239302
http://dx.doi.org/10.1126/sciadv.abd7563