Tumor Infiltrating Effector Memory Antigen-Specific CD8(+) T Cells Predict Response to Immune Checkpoint Therapy

Immune checkpoint therapy (ICT) results in durable responses in individuals with some cancers, but not all patients respond to treatment. ICT improves CD8(+) cytotoxic T lymphocyte (CTL) function, but changes in tumor antigen-specific CTLs post-ICT that correlate with successful responses have not b...

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Detalles Bibliográficos
Autores principales: Principe, Nicola, Kidman, Joel, Goh, Siting, Tilsed, Caitlin M., Fisher, Scott A., Fear, Vanessa S., Forbes, Catherine A., Zemek, Rachael M., Chopra, Abha, Watson, Mark, Dick, Ian M., Boon, Louis, Holt, Robert A., Lake, Richard A., Nowak, Anna K., Lesterhuis, Willem Joost, McDonnell, Alison M., Chee, Jonathan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688517/
https://www.ncbi.nlm.nih.gov/pubmed/33262762
http://dx.doi.org/10.3389/fimmu.2020.584423

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7688517/
https://www.ncbi.nlm.nih.gov/pubmed/33262762
http://dx.doi.org/10.3389/fimmu.2020.584423

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