Simultaneous blood and brain microdialysis in a free-moving mouse to test blood-brain barrier permeability of chemicals

Neurotoxic chemicals that pass through the blood-brain barrier (BBB) can influence brain function. Efficient methods to test the permeability of the BBB to specific chemicals would facilitate identification of potentially neurotoxic agents. We report here a simultaneous blood and brain microdialysis...

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Detalles Bibliográficos
Autores principales: Umezu, Toyoshi, Sano, Tomoharu, Hayashi, Junko, Shibata, Yasuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689036/
https://www.ncbi.nlm.nih.gov/pubmed/33294385
http://dx.doi.org/10.1016/j.toxrep.2020.10.023