TNFSF15 Promotes Antimicrobial Pathways in Human Macrophages and These Are Modulated by TNFSF15 Disease-Risk Variants

BACKGROUND & AIMS: TNFSF15 genetic variants leading to increased TNF superfamily member 15 (TNFSF15) expression confer risk for inflammatory bowel disease (IBD), and TNFSF15 is being explored as a therapeutic target in IBD patients. Although the focus for TNFSF15-mediated inflammatory outcomes h...

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Detalles Bibliográficos
Autores principales: Sun, Rui, Hedl, Matija, Abraham, Clara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689184/
https://www.ncbi.nlm.nih.gov/pubmed/32827707
http://dx.doi.org/10.1016/j.jcmgh.2020.08.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689184/
https://www.ncbi.nlm.nih.gov/pubmed/32827707
http://dx.doi.org/10.1016/j.jcmgh.2020.08.003

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