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Tandospirone, a Partial 5-HT(1A) Receptor Agonist, Administered Systemically or Into Anterior Cingulate Attenuates Repetitive Behaviors in Shank3B Mice
BACKGROUND: Several cases of autism spectrum disorder have been linked to mutations in the SHANK3 gene. Haploinsufficiency of the SHANK3 gene contributes to Phelan-McDermid syndrome, which often presents an autism spectrum disorder phenotype along with moderate to severe intellectual disability. A S...
Autores principales: | Dunn, Jeffrey T, Mroczek, Jessica, Patel, Harsh R, Ragozzino, Michael E |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689206/ https://www.ncbi.nlm.nih.gov/pubmed/32619232 http://dx.doi.org/10.1093/ijnp/pyaa047 |
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