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Downregulation of Sirt1 is correlated to upregulation of p53 and increased apoptosis in epicardial adipose tissue of patients with coronary artery disease

The higher expression level of p53 in epithelial adipose tissue (EAT) has previously been reported in atherosclerosis. Since we hypothesized that the expression of p53 is modulated by Sirt1, the aim of this study was to determine the expression levels of Sirt1 and p53 and to investigate their correl...

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Detalles Bibliográficos
Autores principales: Khanahmadi, Mahdieh, Manafi, Babak, Tayebinia, Heidar, Karimi, Jamshid, Khodadadi, Iraj
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Leibniz Research Centre for Working Environment and Human Factors 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689241/
https://www.ncbi.nlm.nih.gov/pubmed/33250679
http://dx.doi.org/10.17179/excli2020-2423