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Phosphorylation Modifications Regulating Cardiac Protein Quality Control Mechanisms

Many forms of cardiac disease, including heart failure, present with inadequate protein quality control (PQC). Pathological conditions often involve impaired removal of terminally misfolded proteins. This results in the formation of large protein aggregates, which further reduce cellular viability a...

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Detalles Bibliográficos
Autores principales: Mishra, Sumita, Dunkerly-Eyring, Brittany L., Keceli, Gizem, Ranek, Mark J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689282/
https://www.ncbi.nlm.nih.gov/pubmed/33281625
http://dx.doi.org/10.3389/fphys.2020.593585