Cargando…
LRP2 controls sonic hedgehog-dependent differentiation of cardiac progenitor cells during outflow tract formation
Conotruncal malformations are a major cause of congenital heart defects in newborn infants. Recently, genetic screens in humans and in mouse models have identified mutations in LRP2, a multi-ligand receptor, as a novel cause of a common arterial trunk, a severe form of outflow tract (OFT) defect. Ye...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689296/ https://www.ncbi.nlm.nih.gov/pubmed/32901292 http://dx.doi.org/10.1093/hmg/ddaa200 |