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Establishment and application of a predictive model for gefitinib-induced severe rash based on pharmacometabolomic profiling and polymorphisms of transporters in non-small cell lung cancer

BACKGROUND: Rash is a well-known predictor of survival for patients with gefitinib therapy with non-small cell lung cancer (NSCLC). However, whether patients with more severe rash obtain the more survival benefits from gefitinib is still unknown, and predicted model for severe rash is needed. METHOD...

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Detalles Bibliográficos
Autores principales: Guan, Shaoxing, Chen, Xi, Xin, Shuang, Liu, Shu, Yang, Yunpeng, Fang, Wenfeng, Huang, Yan, Zhao, Hongyun, Zhu, Xia, Zhuang, Wei, Wang, Fei, Feng, Wei, Zhang, Xiaoxu, Huang, Min, Wang, Xueding, Zhang, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689337/
https://www.ncbi.nlm.nih.gov/pubmed/33221684
http://dx.doi.org/10.1016/j.tranon.2020.100951