Relevance of PSGL-1 Expression in B Cell Development and Activation

PSGL-1 is expressed in all plasma cells, but only in a small percentage of circulating B cells. Patients with systemic sclerosis (SSc) show reduced expression of PSGL-1 in B cells and increased prevalence of pulmonary arterial hypertension. PSGL-1 deficiency leads to a SSc-like syndrome and SSc-asso...

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Detalles Bibliográficos
Autores principales: González-Tajuelo, Rafael, González-Sánchez, Elena, Silván, Javier, Muñoz-Callejas, Antonio, Vicente-Rabaneda, Esther, García-Pérez, Javier, Castañeda, Santos, Urzainqui, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689347/
https://www.ncbi.nlm.nih.gov/pubmed/33281818
http://dx.doi.org/10.3389/fimmu.2020.588212

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689347/
https://www.ncbi.nlm.nih.gov/pubmed/33281818
http://dx.doi.org/10.3389/fimmu.2020.588212

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