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Tumor treating fields (TTFields) impairs aberrant glycolysis in glioblastoma as evaluated by [(18)F]DASA-23, a non-invasive probe of pyruvate kinase M2 (PKM2) expression

Despite the anti-proliferative and survival benefits from tumor treating fields (TTFields) in human glioblastoma (hGBM), little is known about the effects of this form of alternating electric fields therapy on the aberrant glycolysis of hGBM. [(18)F]FDG is the most common radiotracer in cancer metab...

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Detalles Bibliográficos
Autores principales: Patel, Chirag B., Beinat, Corinne, Xie, Yuanyang, Chang, Edwin, Gambhir, Sanjiv S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689378/
https://www.ncbi.nlm.nih.gov/pubmed/33221711
http://dx.doi.org/10.1016/j.neo.2020.11.003