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Integration of Transcriptomics and Metabolomics Reveals the Antitumor Mechanism Underlying Shikonin in Colon Cancer

Colorectal cancer is a common malignancy occurring in the digestive system, which is the third common cause of cancer mortality in developed countries. Shikonin, a naphthoquinone compound extracted from the root of Lithospermum erythrorhizon, is extensively reported to exert antitumor activity again...

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Detalles Bibliográficos
Autores principales: Chen, Yang, Gao, Yun, Yi, Xiaojiao, Zhang, Jinghui, Chen, Zhongjian, Wu, Yongjiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689381/
https://www.ncbi.nlm.nih.gov/pubmed/33281602
http://dx.doi.org/10.3389/fphar.2020.544647