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Secreted sphingomyelins modulate low mammary cancer incidence observed in certain mammals

Determining mechanisms that naturally protect species from developing cancer is critical in order to prevent and treat cancer. Here, we describe a novel cancer-suppressing mechanism, via the secretion of bioactive factors by mammary cells, that is present in domesticated mammals with a low mammary c...

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Detalles Bibliográficos
Autores principales: Ledet, Melissa M., Harman, Rebecca M., Fan, Jennifer C., Schmitt-Matzen, Emily, Diaz-Rubio, Maria Elena, Zhang, Sheng, Van de Walle, Gerlinde R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689471/
https://www.ncbi.nlm.nih.gov/pubmed/33239740
http://dx.doi.org/10.1038/s41598-020-77639-1