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Multiple myeloma hinders erythropoiesis and causes anaemia owing to high levels of CCL3 in the bone marrow microenvironment

Anaemia is the most common complication of myeloma and is associated with worse clinical outcomes. Although marrow replacement with myeloma cells is widely considered a mechanistic rationale for anaemia, the exact process has not been fully understood. Our large cohort of 1363 myeloma patients had m...

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Detalles Bibliográficos
Autores principales: Liu, Lanting, Yu, Zhen, Cheng, Hui, Mao, Xuehan, Sui, Weiwei, Deng, Shuhui, Wei, Xiaojing, Lv, Junqiang, Du, Chenxing, Xu, Jie, Huang, Wenyang, Xia, Shuang, An, Gang, Zhou, Wen, Ma, Xiaoke, Cheng, Tao, Qiu, Lugui, Hao, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689499/
https://www.ncbi.nlm.nih.gov/pubmed/33239656
http://dx.doi.org/10.1038/s41598-020-77450-y