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A Key GWAS-Identified Genetic Variant Contributes to Hyperlipidemia by Upregulating miR-320a
It has been unclear whether the elevated levels of the circulating miR-320a in patients with coronary artery disease is due to environmental influence or genetic basis. By recombinant adeno-associated virus (rAAV)-mediated loss- and gain-of-function studies in the mouse liver, we revealed that eleva...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689551/ https://www.ncbi.nlm.nih.gov/pubmed/33294796 http://dx.doi.org/10.1016/j.isci.2020.101788 |