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Toward Developing Intuitive Rules for Protein Variant Effect Prediction Using Deep Mutational Scanning Data
[Image: see text] Protein structure and function can be severely altered by even a single amino acid mutation. Predictions of mutational effects using extensive artificial intelligence (AI)-based models, although accurate, remain as enigmatic as the experimental observations in terms of improving in...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689672/ https://www.ncbi.nlm.nih.gov/pubmed/33251402 http://dx.doi.org/10.1021/acsomega.0c02402 |