Reversal of Regioselectivity in Zinc‐Dependent Medium‐Chain Alcohol Dehydrogenase from Rhodococcus erythropolis toward Octanone Derivatives

The zinc‐dependent medium‐chain alcohol dehydrogenase from Rhodococcus erythropolis (ReADH) is one of the most versatile biocatalysts for the stereoselective reduction of ketones to chiral alcohols. Despite its known broad substrate scope, ReADH only accepts carbonyl substrates with either a methyl...

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Detalles Bibliográficos
Autores principales: Dhoke, Gaurao V., Ensari, Yunus, Hacibaloglu, Dinc Yasat, Gärtner, Anna, Ruff, Anna Joëlle, Bocola, Marco, Davari, Mehdi D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689849/
https://www.ncbi.nlm.nih.gov/pubmed/32415803
http://dx.doi.org/10.1002/cbic.202000247

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689849/
https://www.ncbi.nlm.nih.gov/pubmed/32415803
http://dx.doi.org/10.1002/cbic.202000247

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