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Reversal of Regioselectivity in Zinc‐Dependent Medium‐Chain Alcohol Dehydrogenase from Rhodococcus erythropolis toward Octanone Derivatives
The zinc‐dependent medium‐chain alcohol dehydrogenase from Rhodococcus erythropolis (ReADH) is one of the most versatile biocatalysts for the stereoselective reduction of ketones to chiral alcohols. Despite its known broad substrate scope, ReADH only accepts carbonyl substrates with either a methyl...
Autores principales: | Dhoke, Gaurao V., Ensari, Yunus, Hacibaloglu, Dinc Yasat, Gärtner, Anna, Ruff, Anna Joëlle, Bocola, Marco, Davari, Mehdi D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689849/ https://www.ncbi.nlm.nih.gov/pubmed/32415803 http://dx.doi.org/10.1002/cbic.202000247 |
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