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‘Resistance is futile?’ – paradoxical inhibitory effects of K(ATP) channel closure in glucagon‐secreting α‐cells
By secreting insulin and glucagon, the β‐ and α‐cells of the pancreatic islets play a central role in the regulation of systemic metabolism. Both cells are equipped with ATP‐regulated potassium (K(ATP)) channels that are regulated by the intracellular ATP/ADP ratio. In β‐cells, K(ATP) channels are a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7689873/ https://www.ncbi.nlm.nih.gov/pubmed/32716554 http://dx.doi.org/10.1113/JP279775 |