Macrophage to myofibroblast transition contributes to subretinal fibrosis secondary to neovascular age-related macular degeneration

BACKGROUND: Macular fibrosis causes irreparable vision loss in neovascular age-related macular degeneration (nAMD) even with anti-vascular endothelial growth factor (VEGF) therapy. Inflammation is known to play an important role in macular fibrosis although the underlying mechanism remains poorly de...

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Detalles Bibliográficos
Autores principales: Little, Karis, Llorián-Salvador, Maria, Tang, Miao, Du, Xuan, Marry, Stephen, Chen, Mei, Xu, Heping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690191/
https://www.ncbi.nlm.nih.gov/pubmed/33239022
http://dx.doi.org/10.1186/s12974-020-02033-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690191/
https://www.ncbi.nlm.nih.gov/pubmed/33239022
http://dx.doi.org/10.1186/s12974-020-02033-7

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