Biomineralized metal–organic framework nanoparticles enable a primer exchange reaction-based DNA machine to work in living cells for imaging and gene therapy

Sensitive tumor imaging and precise tumor therapy play critical roles in the cancer combat. Herein, we build a DNA machine based on a primer exchange reaction (PER) for mRNA imaging and gene therapy. By using zeolitic imidazolate framework-8 nanoparticles (ZIF-8 NPs) to co-deliver the components inc...

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Detalles Bibliográficos
Autores principales: Zhang, Juan, He, Mengyun, Nie, Cunpeng, He, Manman, Pan, Qingshan, Liu, Chang, Hu, Yanlei, Chen, Tingting, Chu, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690219/
https://www.ncbi.nlm.nih.gov/pubmed/33250978
http://dx.doi.org/10.1039/d0sc00339e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690219/
https://www.ncbi.nlm.nih.gov/pubmed/33250978
http://dx.doi.org/10.1039/d0sc00339e

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