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Fisetin ameliorates atherosclerosis by regulating PCSK9 and LOX-1 in apoE(-/-) mice

The purpose of the current study was to investigate the mechanism by which fisetin improves atherosclerosis (AS) by regulating lipid metabolism and senescence in apolipoprotein E-deficient (apoE(-/-)) mice. An AS model was established by feeding apoE(-/-) mice a high-fat diet. Mice were randomly div...

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Detalles Bibliográficos
Autores principales: Yan, Li, Jia, Qingling, Cao, Hui, Chen, Chuan, Xing, Sanli, Huang, Yan, Shen, Dingzhu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690243/
https://www.ncbi.nlm.nih.gov/pubmed/33262811
http://dx.doi.org/10.3892/etm.2020.9457