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Human P2X7 Receptor Causes Cycle Arrest in RPMI-8226 Myeloma Cells to Alter the Interaction with Osteoblasts and Osteoclasts

Multiple myeloma is a malignant expansion of plasma cells and aggressively affects bone health. We show that P2X7 receptor altered myeloma growth, which affects primary bone cells in vitro. Expression on six human myeloma cell lines confirmed the heterogeneity associated with P2X7 receptor. Pharmaco...

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Detalles Bibliográficos
Autores principales: Agrawal, Ankita, S. Kruse, Lars, J. Vangsted, Annette, Gartland, Alison, R. Jørgensen, Niklas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690412/
https://www.ncbi.nlm.nih.gov/pubmed/33105696
http://dx.doi.org/10.3390/cells9112341