Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier

The blood-testis barrier (BTB) formed by adjacent Sertoli cells (SCs) limits the entry of many chemicals into seminiferous tubules. Differences in rodent and human substrate-transporter selectivity or kinetics can misrepresent conclusions drawn using rodent in vitro models. Therefore, human in vitro...

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Detalles Bibliográficos
Autores principales: Hau, Raymond K., Miller, Siennah R., Wright, Stephen H., Cherrington, Nathan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690448/
https://www.ncbi.nlm.nih.gov/pubmed/33105674
http://dx.doi.org/10.3390/pharmaceutics12111005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690448/
https://www.ncbi.nlm.nih.gov/pubmed/33105674
http://dx.doi.org/10.3390/pharmaceutics12111005

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