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Generation of a hTERT-Immortalized Human Sertoli Cell Model to Study Transporter Dynamics at the Blood-Testis Barrier

The blood-testis barrier (BTB) formed by adjacent Sertoli cells (SCs) limits the entry of many chemicals into seminiferous tubules. Differences in rodent and human substrate-transporter selectivity or kinetics can misrepresent conclusions drawn using rodent in vitro models. Therefore, human in vitro...

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Detalles Bibliográficos
Autores principales:	Hau, Raymond K., Miller, Siennah R., Wright, Stephen H., Cherrington, Nathan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690448/ https://www.ncbi.nlm.nih.gov/pubmed/33105674 http://dx.doi.org/10.3390/pharmaceutics12111005

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