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Enrichment Environment Positively Influences Depression- and Anxiety-Like Behavior in Serotonin Transporter Knockout Rats through the Modulation of Neuroplasticity, Spine, and GABAergic Markers

The serotonin transporter (5-HTT in humans, SERT in rodents) is the main regulator of serotonergic transmission in the brain. The short allelic variant of the 5-HTT gene is in humans associated with psychopathologies and may enhance the vulnerability to develop depression after exposure to stressful...

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Detalles Bibliográficos
Autores principales: Sbrini, Giulia, Brivio, Paola, Bosch, Kari, Homberg, Judith Regina, Calabrese, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690660/
https://www.ncbi.nlm.nih.gov/pubmed/33114023
http://dx.doi.org/10.3390/genes11111248