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Impact of Glycosylation and Species Origin on the Uptake and Permeation of IgGs through the Nasal Airway Mucosa

Although we have recently reported the involvement of neonatal Fc receptor (FcRn) in intranasal transport, the transport mechanisms are far from being elucidated. Ex vivo porcine olfactory tissue, primary cells from porcine olfactory epithelium (OEPC) and the human cell line RPMI 2650 were used to e...

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Detalles Bibliográficos
Autores principales: Ladel, Simone, Maigler, Frank, Flamm, Johannes, Schlossbauer, Patrick, Handl, Alina, Hermann, Rebecca, Herzog, Helena, Hummel, Thomas, Mizaikoff, Boris, Schindowski, Katharina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690786/
https://www.ncbi.nlm.nih.gov/pubmed/33114132
http://dx.doi.org/10.3390/pharmaceutics12111014