Cargando…
Impact of Glycosylation and Species Origin on the Uptake and Permeation of IgGs through the Nasal Airway Mucosa
Although we have recently reported the involvement of neonatal Fc receptor (FcRn) in intranasal transport, the transport mechanisms are far from being elucidated. Ex vivo porcine olfactory tissue, primary cells from porcine olfactory epithelium (OEPC) and the human cell line RPMI 2650 were used to e...
Autores principales: | Ladel, Simone, Maigler, Frank, Flamm, Johannes, Schlossbauer, Patrick, Handl, Alina, Hermann, Rebecca, Herzog, Helena, Hummel, Thomas, Mizaikoff, Boris, Schindowski, Katharina |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690786/ https://www.ncbi.nlm.nih.gov/pubmed/33114132 http://dx.doi.org/10.3390/pharmaceutics12111014 |
Ejemplares similares
-
Improved In Vitro Model for Intranasal Mucosal Drug Delivery: Primary Olfactory and Respiratory Epithelial Cells Compared with the Permanent Nasal Cell Line RPMI 2650
por: Ladel, Simone, et al.
Publicado: (2019) -
Allogenic Fc Domain-Facilitated Uptake of IgG in Nasal Lamina Propria: Friend or Foe for Intranasal CNS Delivery?
por: Ladel, Simone, et al.
Publicado: (2018) -
Selective CNS Targeting and Distribution with a Refined Region-Specific Intranasal Delivery Technique via the Olfactory Mucosa
por: Maigler, Frank, et al.
Publicado: (2021) -
Data of rational process optimization for the production of a full IgG and its Fab fragment from hybridoma cells
por: Röhm, Martina, et al.
Publicado: (2016) -
IgGs drive COVID-19 myeloid hyperinflammation
por: Park, Matthew D.
Publicado: (2020)