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USP1 Regulates TAZ Protein Stability Through Ubiquitin Modifications in Breast Cancer

SIMPLE SUMMARY: Triple-Negative breast cancer (TNBC) is the most aggressive form of breast cancer in women. Targeted therapies for the treatment of this disease are severely lacking. Through mechanistic studies of the key component of Hippo signaling pathway, Transcriptional co-activator with PDZ-bi...

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Detalles Bibliográficos
Autores principales: Mussell, Ashley, Shen, He, Chen, Yanmin, Mastri, Michalis, Eng, Kevin H., Bshara, Wiam, Frangou, Costa, Zhang, Jianmin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690829/
https://www.ncbi.nlm.nih.gov/pubmed/33114077
http://dx.doi.org/10.3390/cancers12113090