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A validated mouse model capable of recapitulating the protective effects of female sex hormones on ascending aortic aneurysms and dissections (AADs)

Fewer females develop AADs (ascending aortic aneurysms and dissections) and the reasons for this protection remain poorly understood. The present study seeks to develop a mouse model that may be utilized to address this sexual dimorphism. Adult normolipidemic mice were challenged with BAPN (β‐aminop...

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Detalles Bibliográficos
Autores principales: Qi, Xiaoyan, Wang, Fen, Chun, Changzoon, Saldarriaga, Lennon, Jiang, Zhisheng, Pruitt, Eric Y., Arnaoutakis, George J., Upchurch, Gilbert R., Jiang, Zhihua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7690909/
https://www.ncbi.nlm.nih.gov/pubmed/33242364
http://dx.doi.org/10.14814/phy2.14631