Cargando…

Predicting Preference of Transcription Factors for Methylated DNA Using Sequence Information

Transcription factors play key roles in cell-fate decisions by regulating 3D genome conformation and gene expression. The traditional view is that methylation of DNA hinders transcription factors binding to them, but recent research has shown that many transcription factors prefer to bind to methyla...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Meng-Lu, Su, Wei, Wang, Jia-Shu, Yang, Yu-He, Yang, Hui, Lin, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691157/
https://www.ncbi.nlm.nih.gov/pubmed/33294291
http://dx.doi.org/10.1016/j.omtn.2020.07.035