Notochordal-Cell-Derived Exosomes Induced by Compressive Load Inhibit Angiogenesis via the miR-140-5p/Wnt/β-Catenin Axis

Angiogenesis is a pathological signature of intervertebral disc degeneration (IDD). Accumulating evidence has shown that notochordal cells (NCs) play an essential role in maintaining intervertebral disc development and homeostasis with inhibitive effect on blood vessel in-growth. However, the anti-a...

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Detalles Bibliográficos
Autores principales: Sun, Zhen, Liu, Bing, Liu, Zhi-Heng, Song, Wen, Wang, Dong, Chen, Bei-Yu, Fan, Jing, Xu, Zhe, Geng, Dan, Luo, Zhuo-Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691158/
https://www.ncbi.nlm.nih.gov/pubmed/33294295
http://dx.doi.org/10.1016/j.omtn.2020.10.021

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691158/
https://www.ncbi.nlm.nih.gov/pubmed/33294295
http://dx.doi.org/10.1016/j.omtn.2020.10.021

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