Cargando…
Notochordal-Cell-Derived Exosomes Induced by Compressive Load Inhibit Angiogenesis via the miR-140-5p/Wnt/β-Catenin Axis
Angiogenesis is a pathological signature of intervertebral disc degeneration (IDD). Accumulating evidence has shown that notochordal cells (NCs) play an essential role in maintaining intervertebral disc development and homeostasis with inhibitive effect on blood vessel in-growth. However, the anti-a...
Autores principales: | Sun, Zhen, Liu, Bing, Liu, Zhi-Heng, Song, Wen, Wang, Dong, Chen, Bei-Yu, Fan, Jing, Xu, Zhe, Geng, Dan, Luo, Zhuo-Jing |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Gene & Cell Therapy
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691158/ https://www.ncbi.nlm.nih.gov/pubmed/33294295 http://dx.doi.org/10.1016/j.omtn.2020.10.021 |
Ejemplares similares
-
Exosomes Derived From Hypoxic Colorectal Cancer Cells Promote Angiogenesis Through Wnt4-Induced β-Catenin Signaling in Endothelial Cells
por: Huang, Zhe, et al.
Publicado: (2017) -
Wnt5 is required for notochord cell intercalation in the ascidian Halocynthia roretzi
por: Niwano, Tomoko, et al.
Publicado: (2009) -
Evolution of the notochord
por: Annona, Giovanni, et al.
Publicado: (2015) -
Notochord vacuoles absorb compressive bone growth during zebrafish spine formation
por: Bagwell, Jennifer, et al.
Publicado: (2020) -
Notochord vacuoles are lysosome-related organelles that function in axis and spine morphogenesis
por: Ellis, Kathryn, et al.
Publicado: (2013)