Neuroprotective Effect of Oridonin on Traumatic Brain Injury via Inhibiting NLRP3 Inflammasome in Experimental Mice

NLRP3 inflammasome has been considered as an important contributor to inflammation and neuronal death after traumatic brain injury (TBI). Oridonin (Ori), the major active ingredient of Chinese herbal medicine Rabdosia rubescens, has been proved to be a covalent NLRP3 inhibitor with strong anti-infla...

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Detalles Bibliográficos
Autores principales: Yan, Chaolong, Yan, Huiying, Mao, Jiannan, Liu, Yutong, Xu, Li, Zhao, Hongting, Shen, Jiaqi, Cao, Yan, Gao, Yongyue, Li, Kuanyu, Jin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691250/
https://www.ncbi.nlm.nih.gov/pubmed/33281541
http://dx.doi.org/10.3389/fnins.2020.557170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691250/
https://www.ncbi.nlm.nih.gov/pubmed/33281541
http://dx.doi.org/10.3389/fnins.2020.557170

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