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In vitro model of distinct catabolic and inflammatory response patterns of endothelial cells to intervertebral disc cell degeneration

To evaluate dominant cell-to-cell paracrine interactions, including those of human annulus fibrosus (AF), nucleus pulposus (NP), and endothelial cells (ECs), in the production of inflammatory mediators and catabolic enzymes, ECs was cultured in soluble factors derived from AF or NP cells (AFCM or NP...

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Detalles Bibliográficos
Autores principales: Hwang, Min Ho, Son, Hyeong-Guk, Kim, Joohan, Choi, Hyuk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691345/
https://www.ncbi.nlm.nih.gov/pubmed/33244116
http://dx.doi.org/10.1038/s41598-020-77785-6