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In vitro model of distinct catabolic and inflammatory response patterns of endothelial cells to intervertebral disc cell degeneration
To evaluate dominant cell-to-cell paracrine interactions, including those of human annulus fibrosus (AF), nucleus pulposus (NP), and endothelial cells (ECs), in the production of inflammatory mediators and catabolic enzymes, ECs was cultured in soluble factors derived from AF or NP cells (AFCM or NP...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691345/ https://www.ncbi.nlm.nih.gov/pubmed/33244116 http://dx.doi.org/10.1038/s41598-020-77785-6 |