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Integron gene cassettes harboring novel variants of d-alanine-d-alanine ligase confer high-level resistance to d-cycloserine

Antibiotic resistance poses an increasing threat to global health. To tackle this problem, the identification of principal reservoirs of antibiotic resistance genes (ARGs) plus an understanding of drivers for their evolutionary selection are important. During a PCR-based screen of ARGs associated wi...

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Detalles Bibliográficos
Autores principales: Rahman, Md. Ajijur, Kaiser, Frank, Jamshidi, Shirin, Freitas Monteiro, Marta, Rahman, Khondaker Miraz, Mullany, Peter, Roberts, Adam P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691350/
https://www.ncbi.nlm.nih.gov/pubmed/33244063
http://dx.doi.org/10.1038/s41598-020-77377-4