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Cytosolic serine hydroxymethyltransferase controls lung adenocarcinoma cells migratory ability by modulating AMP kinase activity

Nutrient utilization and reshaping of metabolism in cancer cells is a well-known driver of malignant transformation. Less clear is the influence of the local microenvironment on metastasis formation and choice of the final organ to invade. Here we show that the level of the amino acid serine in the...

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Detalles Bibliográficos
Autores principales: Bouzidi, Amani, Magnifico, Maria Chiara, Paiardini, Alessandro, Macone, Alberto, Boumis, Giovanna, Giardina, Giorgio, Rinaldo, Serena, Liberati, Francesca Romana, Lauro, Clotilde, Limatola, Cristina, Lanzillotta, Chiara, Tramutola, Antonella, Perluigi, Marzia, Sgarbi, Gianluca, Solaini, Giancarlo, Baracca, Alessandra, Paone, Alessio, Cutruzzolà, Francesca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691363/
https://www.ncbi.nlm.nih.gov/pubmed/33243973
http://dx.doi.org/10.1038/s41419-020-03215-0