Fibrinolysis-resistant carbonylated fibrin detected in thrombi attached to the vascular wall of abdominal aortic aneurysms

In this study, we investigated how carbonylation of fibrinogen by acrolein modified its indispensable function to enhance fibrinolysis after being converted to fibrin and contributed to generating a fibrinolysis-resistant fibrin clot. Acrolein-treated fibrinogen was subjected to tissue plasminogen a...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Yuko, Tanaka, Hiroki, Horinouchi, Takahiro, Sano, Hideto, Honkura, Naoki, Unno, Naoki, Miwa, Soichi, Urano, Tetsumei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691368/
https://www.ncbi.nlm.nih.gov/pubmed/33244022
http://dx.doi.org/10.1038/s41598-020-77582-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691368/
https://www.ncbi.nlm.nih.gov/pubmed/33244022
http://dx.doi.org/10.1038/s41598-020-77582-1

Ejemplares similares