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Population Pharmacokinetic Model of Plasma and Cellular Mycophenolic Acid in Kidney Transplant Patients from the CIMTRE Study

BACKGROUND AND OBJECTIVE: Mycophenolate mofetil is widely used in kidney transplant recipients. Mycophenolate mofetil is hydrolysed by blood esterases to mycophenolic acid (MPA), the active drug. Although MPA therapeutic drug monitoring has been recommended to optimise the treatment efficacy by the...

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Detalles Bibliográficos
Autores principales: Riglet, François, Bertrand, Julie, Barrail-Tran, Aurélie, Verstuyft, Céline, Michelon, Hugues, Benech, Henri, Durrbach, Antoine, Furlan, Valérie, Barau, Caroline
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691413/
https://www.ncbi.nlm.nih.gov/pubmed/33025511
http://dx.doi.org/10.1007/s40268-020-00319-y