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Population Pharmacokinetic Model of Plasma and Cellular Mycophenolic Acid in Kidney Transplant Patients from the CIMTRE Study
BACKGROUND AND OBJECTIVE: Mycophenolate mofetil is widely used in kidney transplant recipients. Mycophenolate mofetil is hydrolysed by blood esterases to mycophenolic acid (MPA), the active drug. Although MPA therapeutic drug monitoring has been recommended to optimise the treatment efficacy by the...
Autores principales: | Riglet, François, Bertrand, Julie, Barrail-Tran, Aurélie, Verstuyft, Céline, Michelon, Hugues, Benech, Henri, Durrbach, Antoine, Furlan, Valérie, Barau, Caroline |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691413/ https://www.ncbi.nlm.nih.gov/pubmed/33025511 http://dx.doi.org/10.1007/s40268-020-00319-y |
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