Targeting Mitochondrial Complex I Overcomes Chemoresistance in High OXPHOS Pancreatic Cancer

Mitochondrial respiration (oxidative phosphorylation, OXPHOS) is an emerging target in currently refractory cancers such as pancreatic ductal adenocarcinoma (PDAC). However, the variability of energetic metabolic adaptations between PDAC patients has not been assessed in functional investigations. I...

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Detalles Bibliográficos
Autores principales: Masoud, Rawand, Reyes-Castellanos, Gabriela, Lac, Sophie, Garcia, Julie, Dou, Samir, Shintu, Laetitia, Abdel Hadi, Nadine, Gicquel, Tristan, El Kaoutari, Abdessamad, Diémé, Binta, Tranchida, Fabrice, Cormareche, Laurie, Borge, Laurence, Gayet, Odile, Pasquier, Eddy, Dusetti, Nelson, Iovanna, Juan, Carrier, Alice
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691450/
https://www.ncbi.nlm.nih.gov/pubmed/33294863
http://dx.doi.org/10.1016/j.xcrm.2020.100143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691450/
https://www.ncbi.nlm.nih.gov/pubmed/33294863
http://dx.doi.org/10.1016/j.xcrm.2020.100143

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