siMTA1-Loaded Exosomes Enhanced Chemotherapeutic Effect of Gemcitabine in Luminal-b Type Breast Cancer by Inhibition of EMT/HIF-α and Autophagy Pathways

Advanced breast cancer holds a poor prognosis for chemotherapy and endocrine therapy resistance. Autophagy is one of the main causes of tumor drug-therapy failure, and increasing evidence shows that EMT also is responsible for that. Metastasis-associated protein1 (MTA1) is up regulated in lots of tu...

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Detalles Bibliográficos
Autores principales: Li, Pengping, Cao, Guodong, Huang, Yuqing, Wu, Wei, Chen, Bo, Wang, Zhenyu, Xiong, Maoming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691572/
https://www.ncbi.nlm.nih.gov/pubmed/33282725
http://dx.doi.org/10.3389/fonc.2020.541262

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691572/
https://www.ncbi.nlm.nih.gov/pubmed/33282725
http://dx.doi.org/10.3389/fonc.2020.541262

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