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N-Glycan Modification in Covid-19 Pathophysiology: In vitro Structural Changes with Limited Functional Effects

In 2014, we reported two siblings with a rare congenital disorder of glycosylation due to mutations in mannosyl-oligosaccharide glucosidase (MOGS). The glycan alteration derived from this disease resulted in an in vitro infection resistance to particular enveloped, N-glycosylation-dependent viruses...

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Detalles Bibliográficos
Autores principales: Nunes-Santos, Cristiane J., Kuehn, Hye Sun, Rosenzweig, Sergio D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691692/
https://www.ncbi.nlm.nih.gov/pubmed/33245474
http://dx.doi.org/10.1007/s10875-020-00905-4