The Poly-E motif in Titin's PEVK region undergoes pH dependent conformational changes

The muscle protein titin plays a crucial role in passive elasticity and the disordered PEVK region within titin is central to that function. The PEVK region is so named due to its high proline, glutamate, valine and lysine content and the high charge density in this region results in a lack of organ...

Descripción completa

Detalles Bibliográficos
Autores principales: Sudarshi Premawardhana, Dassanayake Mudiyanselage, Zhang, Fang, Xu, Jin, Gage, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691732/
https://www.ncbi.nlm.nih.gov/pubmed/33294637
http://dx.doi.org/10.1016/j.bbrep.2020.100859

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691732/
https://www.ncbi.nlm.nih.gov/pubmed/33294637
http://dx.doi.org/10.1016/j.bbrep.2020.100859

Ejemplares similares