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The Poly-E motif in Titin's PEVK region undergoes pH dependent conformational changes
The muscle protein titin plays a crucial role in passive elasticity and the disordered PEVK region within titin is central to that function. The PEVK region is so named due to its high proline, glutamate, valine and lysine content and the high charge density in this region results in a lack of organ...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7691732/ https://www.ncbi.nlm.nih.gov/pubmed/33294637 http://dx.doi.org/10.1016/j.bbrep.2020.100859 |